Research Library
Peptide Research Database
Evidence-based summaries for 25+ research peptides — mechanisms, research areas, storage, and availability.
29 peptides
Ipamorelin
Ipamorelin acetate
A selective growth hormone secretagogue and ghrelin receptor agonist. Considered one of the cleanest GHS peptides due to its minimal effect on cortisol and prolactin.
Sermorelin
GHRH(1-29) · GRF 1-29 NH2
A synthetic analogue of the first 29 amino acids of endogenous growth hormone-releasing hormone (GHRH). Directly stimulates the pituitary to produce and secrete GH.
Tesamorelin
TH9507 · Egrifta (pharmaceutical form)
A stabilized analogue of GHRH with a trans-3-hexenoic acid modification that extends its half-life. Notable for its research in visceral adipose tissue reduction.
CJC-1295
CJC-1295 with DAC · Drug Affinity Complex-GHRH
A long-acting GHRH analogue that covalently binds to albumin in vivo via a Drug Affinity Complex (DAC), extending its half-life from minutes to over a week.
GHRP-2
Growth Hormone Releasing Peptide-2 · Pralmorelin
A synthetic hexapeptide GHSR agonist that strongly stimulates GH release. Also increases appetite via ghrelin receptor activation in the hypothalamus.
Hexarelin
Examorelin · EP-23905
One of the most potent synthetic GHSR agonists. Notable for strong GH release and significant research interest in cardiac protection independent of GH effects.
Retatrutide
LY3437943 · GLP-3 agonist
A first-in-class triple receptor agonist targeting GLP-1, GIP, and glucagon receptors simultaneously. Demonstrated the highest weight loss percentages in Phase 2 clinical trials of any peptide to date.
Semaglutide
Ozempic (weekly) · Wegovy (weight loss)
A highly modified GLP-1 receptor agonist with a C18 fatty diacid modification enabling once-weekly dosing. One of the most extensively studied metabolic peptides.
Tirzepatide
Mounjaro (T2D) · Zepbound (obesity)
A dual GLP-1/GIP receptor agonist. In clinical trials, achieved 20–22% average weight loss at the highest doses, establishing a new benchmark for pharmacological obesity treatment.
AOD-9604
Advanced Obesity Drug · hGH Fragment 176-191
A modified fragment of the C-terminus of human growth hormone (amino acids 176–191) that retains fat-mobilizing properties without the growth-promoting or diabetogenic effects of full hGH.
BPC-157
Body Protection Compound-157 · PL-10
A 15-amino acid peptide derived from a protective protein found in gastric juice. Extensively studied for accelerated healing of tendons, ligaments, muscles, and gut tissue in animal models.
TB-500
Thymosin Beta-4 fragment · Tβ4 (17–23)
A synthetic version of the naturally occurring actin-sequestering protein thymosin beta-4. Promotes tissue repair, reduces inflammation, and enhances cell migration.
Thymosin Alpha-1
Tα1 · Thymalfasin
A 28-amino acid peptide derived from prothymosin alpha. One of the most researched immunomodulatory peptides, used clinically in multiple countries for hepatitis B, C, and immune deficiency.
KPV
Lys-Pro-Val · Alpha-MSH(11-13)
A tripeptide representing the C-terminal fragment of alpha-melanocyte stimulating hormone (α-MSH). Retains the anti-inflammatory properties of α-MSH with superior stability.
Pentadeca Arginate
PDA · BPC-157 arginate salt
A modified form of BPC-157 stabilized as an arginate salt, designed to be more stable at room temperature and suitable for oral administration research.
GHK-Cu
Copper peptide · Copper tripeptide-1
A naturally occurring copper-binding tripeptide found in human plasma. Extensively studied for skin regeneration, wound healing, and anti-aging effects through gene activation.
Epithalon
Epithalamin · Epitalon
A synthetic tetrapeptide based on the pineal gland extract epithalamin. The subject of 35+ years of Soviet and Russian longevity research, primarily studying telomere elongation and lifespan extension in animals.
MOTS-c
Mitochondrial ORF of the 12S rRNA type-c · Mitochondrial-derived peptide
A mitochondria-encoded peptide that acts as a metabolic regulator. Research shows AMPK activation, insulin sensitivity improvements, and potential lifespan extension in animal models.
Dihexa
PNB-0408 · N-hexanoic-Tyr-Ile-(6) aminohexanoic amide
A small peptide derived from angiotensin IV with extremely potent pro-cognitive effects in animal models — reportedly up to 10 million times more potent than BDNF at facilitating synaptogenesis.
Semax
ACTH(4-7)Pro-Gly-Pro · Met-Glu-His-Phe-Pro-Gly-Pro
A synthetic heptapeptide analogue of ACTH(4-7) developed in Russia. Studied extensively for neuroprotection, cognitive enhancement, BDNF upregulation, and stroke treatment.
Selank
TP-7 · Thr-Lys-Pro-Arg-Pro-Gly-Pro
A synthetic heptapeptide analogue of tuftsin developed in Russia. Studied for anxiolytic effects without sedation, memory enhancement, and modulation of BDNF and IL-6.
PT-141
Bremelanotide · Vyleesi (pharmaceutical form)
A melanocortin receptor agonist that acts centrally on hypothalamic pathways to induce sexual arousal. Unlike PDE5 inhibitors, it works through the CNS rather than the vascular system.
Kisspeptin-10
KP-10 · Metastin(112-121)
The shortest bioactive fragment of kisspeptin, a hypothalamic neuropeptide critical for the pulsatile release of GnRH and the initiation of puberty.
Melanotan II
MT-2 · MT-II
A synthetic cyclic analogue of alpha-MSH. Potently activates melanocortin receptors to induce melanogenesis, and also acts centrally to stimulate sexual arousal (leading to the PT-141 discovery).
Melanotan I
Afamelanotide · CUV1647
A linear synthetic analogue of α-MSH with higher selectivity for MC1R than Melanotan II. A pharmaceutical formulation (Scenesse) is approved in Europe and the US for erythropoietic protoporphyria.
Humanin
HN · Humanin-G (S14G variant)
A mitochondria-encoded 21-amino acid peptide with cytoprotective, neuroprotective, and metabolic effects. Plasma levels decline sharply with age.
SS-31
Elamipretide · MTP-131
A cell-permeable tetrapeptide that targets the inner mitochondrial membrane and cardiolipin, protecting mitochondrial structure and function. Under clinical investigation for heart failure and mitochondrial myopathy.
Delta Sleep-Inducing Peptide
DSIP · Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu
A neuropeptide originally isolated from rabbit blood during sleep. Associated with sleep stage modulation, stress adaptation, antioxidant activity, and normalization of hypothalamic-pituitary hormone release.
LL-37
Cathelicidin · Human antimicrobial peptide 18
The only member of the cathelicidin family of host defense peptides in humans. Has broad-spectrum antimicrobial activity and diverse immunomodulatory effects.
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